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April 3, 2014
An evolutionarily biased distribution of miRNA sites toward regulatory genes with high promoter-driven intrinsic transcriptional noise
Background: miRNAs are a major class of regulators of gene expression in metazoans. By targeting cognate mRNAs, miRNAs are involved in regulating most, if not all, biological processes in different cell and tissue types. To better understand how this regulatory potential is allocated among different target gene sets, we carried out a detailed and systematic analysis of miRNA target sites distribution in the mouse genome. Results: We used predicted conserved and non-conserved sites for 779 miRNAs in 3[prime] UTR of 18440 genes downloaded from TargetScan website. Our analysis reveals that 3[prime] UTRs of genes encoding regulatory proteins harbor significantly greater number of miRNA sites than those of non-regulatory, housekeeping and structural, genes. Analysis of miRNA sites for orthologous 3[prime]UTR's in 10 other species indicates that the regulatory genes were maintaining or accruing miRNA sites while non-regulatory genes gradually shed them in the course of evolution. Furthermore, we observed that 3[prime] UTR of genes with higher gene expression variability driven by their promoter sequence content are targeted by many more distinct miRNAs compared to genes with low transcriptional noise. Conclusions: Based on our results we envision a model, which we dubbed "selective inclusion", whereby non-regulatory genes with low transcription noise and stable expression profile lost their sites, while regulatory genes which endure higher transcription noise retained and gained new sites. This adaptation is consistent with the requirements that regulatory genes need to be tightly controlled in order to have precise and optimum protein level to properly function.
Source: BMC Evolutionary Biology
Postdoctoral positions. Evolutionary ecology – phylogenetics. Ecole Normale Supérieure, Paris Several postdoctoral positions are available to work with Hélène Morlon (http://bit.ly/1mCowBn) on a project supported by a five year grant from the European Research Council (ERC), in the general area of evolutionary ecology and phylogenetics. The project integrates across diverse fields (macroevolution, macroecology, community ecology, ecological networks, paleobiology, microbial ecology) with a focus on phylogenetic approaches. Applicants with very diverse backgrounds are encouraged to apply (e.g. mathematics, physics, ecology, evolutionary biology, bioinformatics). Applicants should have solid quantitative, programming, and/or bioinformatics skills, as well as good writing skills. Speaking French is not mandatory. The postdoctoral researchers will work in Hélène Morlon’s group at the Institute of Biology of the Ecole Normale Supérieure (http://bit.ly/Pm2UOx). The IBENS is a multidisciplinary research centre in Biology with more than 300 staff members, conveniently located in the Latin Quarter in downtown Paris. The centre develops research in a wide range of disciplines, including evolutionary biology, ecology, computational biology, genetics, and comparative genomics. Review of applications begins immediately and will continue until the positions are filled. Starting dates are flexible and salaries depend on experience. To apply, please submit: i) a cover letter summarizing research interests and expertise ii) a Curriculum Vitae (including publications), and iii) the names and contact information for at least two references. Questions and application should be sent to Hélène Morlon (email@example.com). Helene Morlon via Gmail
"A few weeks ago I posted the following query "Does anyone have a user-friendly way of inputting data into CLUMPP and DISTRUCT? CLUMPP averages results across STRUCTURE simulations once K has been selected, and DISTRUCT produces the STRUCTURE figure.The challenge is that both are command-line programs, and DISTRUCT mac version seems broken (however, I assume PC version is OK). Dent Earl and Bridgett vonHoldt produced an great solution for processing STRUCTURE output. A similar solution for CLUMPP and DISTRUCT would be most welcome. (Earl, D. A., vonHoldt, B. M., 2011. STRUCTURE HARVESTER: a website and program for visualizing STRUCTURE output and implementing the Evanno method. Conservation Genetics Resources 4, 359-361, doi:10.1007/s12686-011-9548-7.)" Many thanks to those who replied. Their answers are found at http://bit.ly/1jDTglD“ Thanks, Jenny Jennifer Ovenden via Gmail
*UMichigan.Tree.Snail.Evolutionary.Genomics* Postdoctoral opening in the evolutionary genomics of endangered tree snails Position is available beginning October 2014 to work at the University of Michigan (Ann Arbor) with Diarmaid Foighil and Taehwan Lee. We are looking for a highly motivated postdoc with a background in comparative evolutionary genomics to participate in an ongoing research project. It concerns Tahitian tree snail species (Partulidae) that differentially survived a recent mass extinction event and involves working with museum, captive and remnant wild specimens. A background in invertebrate biology is preferred. Demonstrated expertise in next-generation sequencing, bioinformatics and comparative/population genomics is required. The position will be initially funded for one year, with the possibility of renewal for up to two additional years contingent on funding and satisfactory performance. Salary and benefits are competitive. Ann Arbor is a classic American college town. It routinely makes the national “best of” lists (http://bit.ly/PnTEJm) and the University of Michigan’s Department of Ecology & Evolutionary Biology is an excellent academic environment with a dynamic and interactive research program ( http://bit.ly/1cWSoaE). The position is available October 1st 2014, but the start is flexible to some degree. Applicants should have earned their Ph.D. by September 2014 and should send (to the email address below) a cover letter with a statement of background and research interests, a *Curriculum Vitae* and the names and contact details of three references. Review of applications will begin May 1st, 2014; however, the position will remain open until filled. Diarmaid Foighil, University of Michigan Museum of Zoology and Department of Ecology & Evolutionary Biology, 1109 Geddes Avenue, Ann Arbor, MI 48109-1079. firstname.lastname@example.org Phone: 734 647 2193 http://bit.ly/PlUQNS’Foighil-CV-2014.pdf The University of Michigan is an equal opportunity/affirmative action employer. Diarmaid O’Foighil via Gmail
ARTHROPOD GENOMICS 2014 The deadlines for abstract submission and early-bird registration for the 8th Annual Arthropod Genomics Symposium are coming up soon! Register and submit your abstract soon to enjoy the reduced registration rate and take advantage of this opportunity to present your work. The schedule of speakers for AGS 2014 is now available on the website (link below.) Important Dates: Friday, April 4, 2014: Deadline to submit Travel Grant Application for Vector Biologists Thursday, April 17, 2014: Deadline to submit poster abstracts Monday, April 21, 2014: Early-bird registration deadline The 8th Annual Arthropod Genomics Symposium will be held Thursday, June 12 — Saturday, June 14, 2014, hosted by the Institute for Genomic Biology at the University of Illinois at Urbana-Champaign. The link for conference registration and abstract submission is below. Two speakers for each session of the symposium will be selected from among the submitted abstracts. The symposium will feature sessions on the i5k consortium, vector biology, social insects, microbiomes, and population and comparative genomics. Patricia Wittkopp (University of Michigan) will give the keynote lecture on the evolution of promoters and gene regulation in /Drosophila/ on Thursday evening. Judy Willis (University of Georgia) will give a retrospective lecture on 50 years in insect genomics on Friday evening. All are also invited to register for a pre-symposium Epigenomics Workshop to be held on-site on June 12. To register for the Arthropod Genomics Symposium or view more information visit: _http://conferences.igb.illinois.edu/arthropod/_ Arthropod Genomics Symposium 2014 via Gmail
Dear colleagues, We have a 18 month postdoc in Montpellier starting in September 2014 on the wheat transcriptomic response to pathogenic and mutualistic bacteria. Details below. *Postdoc *on Wheat transcriptomics in interaction with mutualistic and pathogenic bacteria 18 month postdoc starting in September 2014 (possibility to change slightly the start date according to eligibility criteria and availability of candidates) *Lab host:*UMR RPB (Resistance of Plants to Bioagressors), IRD (Institute of Research for Development (www.ird.fr ), Montpellier, France. The postdoc will be under the direction of Dr Ralf Koebnik, and will interact also with Dr Lionel Moulin and Dr Florence Wisniewski-Dy. Montpellier is a vibrant, elegant and artistic city in the heart of the Languedoc-Roussillon region, along the shores of the Mediterranean Sea in southern France. *Project:*MIC-CERES (http://bit.ly/1mC8yqO) *Eligibility criteria:* PhD defense less than 2 years ago on 1^st of September 2014 (possibility to increase if we modify starting date). The candidate should not have spent more than 10 months in France during the last 3 years. Eligibility criteria regarding the date of PhD defense might be reconsidered for best fitting candidates. *Postdoc Profile:* We are looking for an enthusiastic young postdoc researcher to work primarily on the bread wheat transcriptomic response to pathogenic (/Xanthomonas/) or mutualistic bacteria (/Azospirillum /and/Burkholderia/). Activities will include RNA extraction of wheat roots and leaves in different inoculation conditions, preparation of samples for RNA sequencing, analyses of RNAseq data and differential gene expression studies in wheat challenged with /Xanthomonas,/ /Azospirillum/ or /Burkholderia/. The candidate will have knowledge on plant transcriptomics, DNA sequence technology and downstream analyses. Background in plant response to microbes would be a plus. Candidates with experience in RNAseq analyses (fastQC, Cutadapt, Tophat/bowtie, or others pipelines) and R language for differential expression analyses (DESeq, DESeq2, edgeR, EBseq) will be favored; otherwise attraction to computing and willingness to learn would be OK. Working language will be English. Basic knowledge of French will facilitate extra-lab communication but is not a must. *Starting salary:*1750 euros per month including social security, pension and job loss benefits. *How to apply:*send a CV and a covering letter describing your suitability for the position before *May 15^th , 2014* to ralf.koebnik[at]ird.fr, lionel.moulin[at]ird.fr and florence.wisniewski[at]univ-lyon1.fr. Lionel Moulin via Gmail
PhD Position for 2014 (3 years) at Victoria University of Wellington Do human actions select for traits that promote invasiveness in animals? *Project Description: * Are humans driving the evolution of invasive species to our own detriment? Humans unwittingly and routinely transport invasive animals and plants around the globe. We hypothesise that this process leads to selection for behavioural traits that enhance invasiveness. The proposed project will test this hypothesis with the Argentine ant, which is listed among the world’s worst invasive species, and considered the ‘Genghis Khan’ of the ant world. The project will study populations from the native and introduced range to assess if: 1) variation in novelty-seeking behaviour exists among populations of ants; 2) this variation in behaviour has a molecular basis; 3) humans have exerted selection pressure on this behaviour; and 4) novelty-seeking promotes invasiveness. The project will combine surveys of ecological communities, behavioural experiments, studies of population genetics, and gene and neurochemical expression. The scale of this analysis - from genes to communities, across four continents - is novel and integrative. This novel research will elucidate an underlying mechanism of how evolution and ecology interact to facilitate invasion success. *The Ideal Candidate:* The ideal candidate will possess experience and ability with molecular genetics techniques, ecology, and statistics. In addition they will be motivated and organized, with a demonstrated capacity to master the broad skill set necessary for the successful completion of a research project. The candidate will be enrolled at Victoria University of Wellington in New Zealand, co-supervised by Dr. Monica Gruber and Prof. Phil Lester. Students will also spend time sampling and undertaking experiments in Argentina, California and Australia. Our national and international team of world-class researchers includes Prof. Alison Mercer (University of Otago), Prof. Gene Robinson and Assoc. Prof. Andy Suarez (University of Illinois at Urbana-Champaign), Dr. Dave Chapple (Monash University) and Dr. Ben Hoffmann (CSIRO Darwin). The project offers a tremendous opportunity to undertake research with world-leaders. *Eligibility and funding:* This opportunity is open to all nationalities. However, candidates must satisfy the English Language Requirements of the University to be eligible for study, and New Zealand criteria for PhD entry. See http://bit.ly/1pSYwDM. The project has sufficient funds for travel, consumables, and international conference attendance. Students will be encouraged to seek funding for personal support and fees through a Victoria University Postgraduate Scholarship. *How to Apply:* Interested applicants are encouraged to make informal enquiries to Dr. Monica Gruber. Please send your Curriculum Vitae, a copy of your academic transcript, a sample of your written scientific work and the names of three referees with a covering letter to: Dr Monica Gruber (email@example.com) Applications will remain open until the position is filled. It would be desirable if the successful applicant were able to start in mid-late 2014. Dates will be flexible for the ideal candidate. Monica Gruber Post-doctoral Research Fellow School of Biological Sciences Victoria University of Wellington PO Box 600, Wellington 6140 New Zealand ph: +64 4 463 5026 / 027 658 9903 Monica.Gruber@vuw.ac.nz via Gmail
Dear colleagues - After receiving overwhelming interest we are excited to announce that we will be teaching three workshops on Methods in Ecological and Evolutionary Genomics at the Mote Tropical Research Laboratory, Florida Keys. Metabarcoding of Symbiont Communities June 15 - June 20 Whole-genome genotyping with 2bRAD June 20 - June 27 Global gene expression profiling with tag-based RNA-Seq June 27 - July 5 To learn more about the specifics of each workshop, please go to our website: http://bit.ly/1mC1V87 Prerequisites The workshops aim at researchers at or above graduate-level actively working in the field of evolution and/or ecology. Practical molecular biology experience, however limited, will be helpful. People with earlier experience with metabarcoding, RNA-seq and RAD are welcome: we use the latest wet-lab methods and analysis protocols developed in the Matz lab, which would be very useful even for an experienced practitioner. The students will need to bring your own laptop with installed R and (for PC users) SSH terminal application. To enroll By April 30, 2014, send an email with “MEGA 2014” in the subject line to all the instructors (Mikhail Matz , Sarah Davies , Rachel Wright ), indicating your interest, and a short description of your research focus (or simply references to your relevant publications). Please specify how likely you are to participate, assuming that you will have to pay the workshop’s fee by May 15 (more details on making payments will be provided here later). Each part of the workshop is limited to 12 participants, first come first serve (assuming the prerequisites are met). Please do not hesitate to contact us should you have any questions. Best regards, Mikhail V. Matz: firstname.lastname@example.org Sarah W. Davies: email@example.com Rachel M. Wright: firstname.lastname@example.org Sarah W. Davies M.Sc. Graduate Student University of Texas at Austin email@example.com via Gmail
PostDoctoral Position at Vanderbilt University - Evolution of Human Birth A postdoctoral position is available in the Rokas lab at Vanderbilt University in Nashville, Tennessee to study the evolutionary genomics of human pregnancy. The ideal candidate will have a strong background in evolutionary genomics, familiarity with scripting languages, a strong publication track record, and a commitment to teamwork. The candidate will join a team of researchers working on developing the computational and conceptual tools necessary for generating a comprehensive evolutionary synthesis of human birth. Through the generation of database tools that will build bridges between evolutionary biologists, geneticists, molecular and developmental biologists, physiologists, obstetricians, and social anthropologists, and by exploiting the power of within and between species genomic comparisons, our research project aims to elucidate the evolution of human birth and pregnancy. The project is funded by the March of Dimes and is in close collaboration with the Abbot lab (http://bit.ly/14CIuVX) and is one of the five major research themes that comprise the March of Dimes Ohio Collaborative (http://bit.ly/1osS8G0). For more information on the Rokas lab: http://bit.ly/17lr3rA For more information on Nashville: http://bit.ly/1osSaxy and http://nyti.ms/1lppUqZ Interested applicants are encouraged to send a CV, an one-page statement of past research accomplishments, and contact information for three references to Antonis Rokas at firstname.lastname@example.org The position is available effective immediately. Best, Antonis Antonis Rokas Associate Professor of Biological Sciences and Biomedical Informatics Cornelius Vanderbilt Chair in Biological Sciences Department of Biological Sciences Vanderbilt University VU Station B 351634, Nashville, TN 37235 Email: antonis.rokas@Vanderbilt.Edu Tel: +1-615-936-3892 Fax: +1-615-343-6707 http://bit.ly/17lr3rA antonis.rokas@Vanderbilt.Edu via Gmail
EMPSEB 20- DEADLINE FOR ABSTRACT SUBMISSION EXTENDED TO 1st OF MAY 2014. Dear Colleagues, The registration deadline for EMPSEB 20 (European meeting of PhD students in evolutionary Biology) has been extended to the 1st of May, giving PhD students at all stages of their research another month to apply! Themeeting will this year be held in La Roche-en-Ardenne in Belgium, from the 1st-6th of September, 2014. Plenary speakers have been confirmed and their talks will cover an array of diverse topics, e.g. sexual and asexual evolution, phenotypic plasticity, non-genetic heredity and epigenetics, complex systems and the evolution of viruses, venoms and stress resistance, involving methods like genomics, proteomics, quantitative genetics or modelling. Details about the confirmed plenaries and how to register can be found on the EMPSEB website: http://empseb20.com/ Registration fee: 350 euro (price includes transport from the airport to La Roche-en-Ardenne, accommodation, and meals during the conference) EMPSEB in a nutshell: EMPSEB provides a platform for PhD students studying evolutionary biology to present their work and meet their peers from all over Europe. It takes place in a different European city each year, and is organised by the PhD students of the host country. The meeting is now an annual tradition that started 19 years ago with the first meeting being held in Zurich, Switzerland in 1995. EMPSEB 20 will last for 5 days and will involve a variety of activities… plus an optional excursion on the last day! A number of senior evolutionary scientists have been selected to give plenary talks and to provide constructive feedback on the participants’ research. All PhD students are required to give a presentation of 15 minutes. Besides the website, you can also follow EMPSEB 20 on Facebook (http://on.fb.me/NeZtbB) and Twitter (http://bit.ly/1odbJV2) Any enquiries can be directed email@example.com We would be very grateful if you could forward this message to anyone you think might be interested. We additionally included an EMPSEB 20 flyer in attachment to easily advertise and spread information about this interesting meeting for PhD students. Best regards, Gwennal Bataille, EMPSEB20 President Gwennal BATAILLE, PhD student - Teaching assistant Earth and Life Institute Universit Catholique de Louvain SST/ELI/ELIB Btiment Carnoy, c.145 Croix du sud 4-5, bte L7.07.04 1348 Louvain-la-Neuve BELGIUM firstname.lastname@example.org via Gmail
Dear colleagues, we are happy to announce that after several delays caused by technical issues, the registration for the 10th Symposium on Cladocera, to be held in the Czech Republic, is finally open. The Symposium on Cladocera, a traditional triannual meeting of researchers studying cladoceran crustaceans, will be held this autumn in the Czech Republic. To celebrate the anniversary 10th meeting, it is fitting to find a spectacular place, and invite special guests. Thus, we will hear talks and admire posters on ecology, evolutionary biology, diversity, systematics, genomics… and many other aspects of these increasingly important model organisms in the recently restored baroque riding hall of the Lednice chateau, one of the landmarks of the UNESCO World Heritage area Lednice-Valtice Cultural Landscape. The keynote talks will be presented by Luc De Meester (Katholieke University Leuven, Belgium) and Michael Lynch (Indiana University, Bloomington, USA). As it became tradition, a special issue of Hydrobiologia will be published as conference proceedings. Apart from an exciting scientific programme, the conference participants and their accompanying persons will get opportunities to admire the historical, natural and oenological treasures of this unique region of Central Europe. To learn more, visit the conference website http://bit.ly/KTFlK6. The registration form allows online payments by credit/debit cards, and you may use it also to book accommodation in one of the hotels in the immediate vicinity of the conference venue. The deadline for early bird discount is on June 15. However, the first 30 registered participants will get a very special surprise gift upon arrival, so we recommend not to wait too long! Those who register early can also expect the best rooms in the conference hotels. Note that you do not need to submit your presentation abstract together with the registration. The abstracts (to be provided by e-mail) can be sent up to July 15. With regards Adam Petrusek & the organization team Pokud je tento e-mail soust obchodnho jednn, Prodovdeck fakulta Univerzity Karlovy v Praze: a) si vyhrazuje prvo jednn kdykoliv ukonit a to i bez uveden dvodu, b) stanovuje, e smlouva mus mt psemnou formu, c) vyluuje pijet nabdky s dodatkem i odchylkou, d) stanovuje, e smlouva je uzavena teprve vslovnm dosaenm shody na vech nleitostech smlouvy. email@example.com via Gmail
Three graduate student positions that apply information from high-density single nucleotide polymorphism (SNP) chips to Atlantic salmon breeding are available in Dr. Elizabeth Bouldings laboratory in the Department of Integrative Biology at the University of Guelph in collaboration with Kelly Cove Salmon Ltd. beginning in May or September 2014. 1) Ph.D. or M.Sc. in applied Atlantic salmon disease genomics/ animal breeding for genetic resistance in commercial strains of Atlantic salmon. The project would involve: a. assisting with annual disease trials in eastern Canada for Infectious salmon anemia (ISA) and Bacterial kidney disease (BKD); b. extractions of high molecular weight DNA from fin clips using modern high-throughput techniques; c. quantitative trait loci (QTL) mapping of ISA and BKD within families of Atlantic salmon using a custom 11K SNP chip; d. calculation of heritabilities and genetic correlations among different disease/parasite-resistance traits; e. assisting a research associate with the calculation of genomic breeding values for the two traits using a proprietary 200 K SNP chip; f. searching the salmon genome for candidate mutations associated with large amount of the variance in disease/parasite resistance. Ideal candidates would have a background in several of: bioinformatics, fish diseases, fish physiology, comparative genomics, molecular laboratory techniques or statistical animal breeding. 2) M.Sc. in applied Atlantic salmon genomics for salmon louse resistance in commercial strains of Atlantic salmon. The project would involve: a. assisting with annual salmon louse parasite challenges in eastern Canada; b. extractions of high molecular weight DNA from fin clips from challenges using modern high-throughput techniques; c. quantitative trait mapping of salmon lice resistance within families of Atlantic salmon using a custom 11K SNP chip d. searching the salmon genome for candidate mutations associated with large amount of the variance in disease/parasite resistance. Ideal candidates would have a background in several of: bioinformatics, fish diseases, fish physiology, comparative genomics, molecular laboratory techniques. 3) M.Sc. in Bioinformatics. Development of new algorithms and R scripts for manipulating data from high density SNP chips and massive phenotypic trait files, developing algorithms and scripts to locate errors in very large pedigrees. Candidates must meet the admission requirement of the University of Guelph M.Sc. program in Bioinformatics. http://bit.ly/1h61i7o Preference will be given to Canadian citizens or residents. Interested candidates should send an email to Professor Elizabeth Boulding firstname.lastname@example.org with the following attachments, preferably as pdf files: 1) All their unofficial university and college transcripts 2) a short version of their resume 3) the names, emails and telephone numbers of 3 referees including at least one previous employer. Elizabeth Grace Boulding Professor University of Guelph, Ontario Canada Department of Integrative Biology 50 Stone Road East University of Guelph Guelph, Ontario N1G 2W1 Canada Email: email@example.com webpage: http://bit.ly/1h61jZ4 firstname.lastname@example.org via Gmail
April 2, 2014
Dear Evoldirians, A lecturer position is opened at the National Museum of Natural History (MNHN) in Paris, France, to work on adaptations, speciation and diversification in Insects. The lecturer will be in charge of curating the Lepidoptera collection of the MNHN. Details (in French only, sorry!) are found here (position n4112). http://bit.ly/1h5YTcQ Please note that EU applicants must already have the ‘qualification pour les fonctions de maitre de confrence’ to be eligible. Non-EU applicants do not need this. Marianne Elias CNRS Researcher UMR 7205 - CNRS Museum National d’Histoire Naturelle 45 rue Buffon, CP50, 75005 Paris phone: +33 1 40 79 37 90 http://bit.ly/Pnhkh3 email@example.com via Gmail
BEAST v2.1.2 We are pleased to announce the release of BEAST v2.1.2. The main improvements are: o BEAUti handles multiple partitions more conveniently o improved package management o fix bug in *BEAST template o added functionality (FASTA support, stochastic distributions, *BEAST operator weighting, etc.) o support for more packages. A more complete list can be found here http://bit.ly/1k1xoTV To install, select the package for your operating system at http://beast2.org/ BEAST core development team Remco Bouckaert via Gmail
—_000_F851097A9DD12A4C9F423C23DCA4E0915E49DFB6UOSDUNMBX3stand_ Content-Type: text/plain; charset=”us-ascii” Content-Transfer-Encoding: quoted-printable Disrupting a pathogen’s metabolism without harming the host Biomedical Sciences Research Complex, University of St Andrews Dr John Mitchell (firstname.lastname@example.org) Dr V Anne Smith (email@example.com) Our aim is to use measures of network structure and robustness to assess the vulnerability of different species of pathogen to anti-infective drugs which target the enzymes essential to the pathogen’s metabolism. As well as better understanding of interventions which will disrupt a pathogen’s metabolism without harming the host, this will also give us insight into human and animal disease. Our increasing understanding of the complex interactions between proteins and small organic molecules allows us to decipher metabolic networks where enzyme-catalysed reactions link together substrates and products to form pathways and cycles. A wealth of bioinformatics data allows us to trace both the variation of networks across different species and also the networks’ evolution. We already have software that simulates metabolism’s evolution. Since we know contemporary biochemistry better than its ancient roots, our simulations work backwards in time, suggesting plausible evolutionary trajectories. This work will allow us to predict the perturbations that would disrupt metabolic networks, and those which could be safely applied. We will be able to categorise the architecture and robustness or fragility of systems across both biological species and time. Potential future applications include the use of synthetic biology to exquisitely design interventions that will affect the pathogen’s metabolism without risk to the host or environment. Funding Notes: The studentship will include a stipend and cover UK and EU tuition fees. International applicants will have to obtain fees from a different source. via Gmail
Linking self-fertilization, dispersal and distribution traits of species: Is Bakerâs law an exception to the rule?
Bakerâs Law (hereafter BL) states that self-compatible organisms are more likely to be successful colonizers after long-distance dispersal than self-incompatible organisms. This simple prediction draws a link between mating-system evolution and diverse fields of ecology and evolution such as dispersal biology and colonization, the evolution of range size and range limits, demography and Allee effect, and invasion biology. However, after >60 years of experimental research and theory development, the accumulated data yield varying, and often contradictory, support of BL. Our working group brings together a diverse array of researchers to assess predictions and assumptions of BL and elucidate ecological, evolutionary, and demographic parameters likely to determine the relationships between mating system, dispersal, and colonization success. To accomplish these goals we will: 1) Compile the voluminous literature on BL. 2) Link the BL data with two extensive databases gathered by prior NESCent support (seed germination and seed traits data; mating system data) and a NCEAS pollen limitation database. These expanded databases will include dispersal, range size, and life-history traits, thereby creating a powerful tool for testing various aspects of the relationship between mating-system and colonization success. 3) Employ macroevolutionary tools to map mating-system and dispersal traits onto the angiosperm phylogeny to assess evolutionary patterns and phylogenetically-corrected trait correlations. 4) Formalize BL using current population genetic theory and dispersal theory. Synthetic products of our working group should elucidate the links between dispersal and mating-system in colonization success, and will influence multiple fields of research in evolution for the foreseeable future.
April 1, 2014
Announcing the sixth annual Lep course, 14- 23 August, 2014. Held at the South West Research Station (SWRS) in the Chirichahua Mountains in SE Arizona (a 2 1/2 hour drive from Tucson), the focus of the Lep course is to train graduate students, post-docs, faculty, and serious citizen-scientists in the classification and identification of adult lepidoptera and their larvae. Topics to be covered include an extensive introduction into adult and larval morphology with a focus on taxonomically-important traits, extensive field work on both adults and larvae, collecting and curatoral techniques, genitalic dissection and preparation, larval classification, use (and abuse) of DNA bar coding, and general issues in lepidoptera systematics, ecology, and evolution. THE LOCATION: With its extensive series of Sky-Island mountain ranges, SE Arizona has the highest lepidoptera diversity in the US. With low desert scrub, oak and mixed oak-pine woodland, lush riparian, juniper, Douglas fir, and mountain meadow habitats all within a 40 minute drive from the station, the SWRS is an ideal location from which to sample this diversity (of both habitats and species). Partial list of Invited instructors (subject to change): John Brown (Smithsonian), Rich Brown (Mississippi Entomological Museum), Marc Epstein (CDFA), Chris Grinter (Denver Museum of Nature & Science), Bruce Walsh (University of Arizona), Dave Wagner (University of Connecticut ) and Ray Nagle (University of Arizona). Fees: Tuition for the course is $1070 for students and $1170 for non-students to be paid by all participants on being informed of their acceptance. Tuition covers overhead costs of the workshop and room and board at the SWRS. Deadline for applications is 14 June 2014. For more information, see http://bit.ly/1hyIDjc or www.lepcourse.org or contact Bruce Walsh at firstname.lastname@example.org You can also see photos and comments from students in previous courses at their facebook site, “2011 Lep Course, SWRS SEAZ”. email@example.com via Gmail
2014 American Genetic Association Presidential Symposium - Evolution and Plasticity: Adaptive responses by species to human-mediated changes to their ecosystems 27-29 June 2014 University of Washington, Seattle STUDENT AWARDS: Awards are available to cover registration ($150), and a limited number to cover both travel and registration ($650). See the AGA website for details - http://bit.ly/1eZIdSq Poster abstracts due April 15 Tentative schedule: Friday 27 June 6 - 9 PM Hosted reception and poster session Saturday 28 June 8 AM - 5 PM Symposium, Day 1 Including: Key Lecture by David Reznick, UC Riverside, “Hard and soft selection revisited:How evolution by natural selection works in the real world” Saturday 28 June 6 - 9 PM Hosted reception and poster session Sunday 29 June 8 AM - 5 PM Symposium, Day 2 Including: Noon brown-bag discussion, “What should conservation biologists and evolutionary biologists know about epigenetics?” moderated by Katie Peichel, AGA president-elect. This will follow a special presentation by Michael Skinner, WSU, “Epigenetic transgenerational inheritance of phenotypic variation in evolution: Lessons from Darwin’s finches” Registration includes all the above activities: General is $200 until May 15th Please visit the AGA website to register and book housing: http://bit.ly/1eZIdSq Robin Waples, AGA President firstname.lastname@example.org via Gmail
LAST REMINDER (application deadline 15 April) Summer school: Dynamics of Infectious Diseases (17-24 August 2014, Finland) Dear Colleagues, We are pleased to invite students and young researchers to the 2014 edition of The Helsinki Summer School on Mathematical Ecology and Evolution, an EMS-ESMTB School in Applied Mathematics, which will focus on the dynamics of infectious diseases. The school will be held between 17 and 24 August 2014 in Turku, Finland. The core program consists of five series of lectures, Odo Diekmann: Population dynamics of infectious diseases Frank Ball: Stochastic models of epidemics Thomas House: Networks and epidemics Michel Langlais: Spatial dynamics of infectious diseases Troy Day: Evolution of hosts and pathogens All young researchers working in mathematical epidemiology, ecology or evolution can apply from all countries, especially from Europe and the Mediterranean. The school is aimed at graduate students of mathematics, but we also welcome students of biology with sufficient background in mathematics, as well as advanced undergraduates and postdocs. The deadline for applications is 15 April 2014. There is no registration fee. For more details and application, see http://bit.ly/1d9zjyJ. Eva Kisdi, Mats Gyllenberg and Elina Numminen via Gmail
BBL: The Duke Lemur Center Database - when, how, and why you can access nearly 50 years of life history data for over 35 prosimian primate species
Wednesday, 12:00 PM at NESCent, Ninth Street and Main Street, Erwin Mill Building, 2024 W. Main Street, Suite A200. For more information, call 919-668-4551
The Genealogical World of Phylogenetic Networks
BMC Evolutionary Biology